Stem cell therapy for Primary Immunodeficiency in the EU

How stem cell therapy works for Primary Immunodeficiency

Cell protocols are considered within an immunology framework to support immune reconstitution in selected primary immunodeficiencies. Treatment at Stem Plus is delivered under a physician-led protocol in our GMP-certified Sofia laboratory, and is designed to complement — not replace — your existing standard of care.

For Primary Immunodeficiency (immunologic), the therapeutic rationale rests less on cells "becoming" new tissue and more on their signalling: modulating inflammation, supporting the local repair environment and recruiting the body's own regenerative response. Cell type, dose and delivery route are matched to your individual assessment rather than applied from a fixed menu.

Cell types used for Primary Immunodeficiency

Depending on your assessment, a Primary Immunodeficiency protocol may draw on:

Why patients choose the EU for Primary Immunodeficiency

• European quality, honest price. €3,000–€8,000 all-in for treatment, versus roughly €15,000–35,000 in the US or Germany.
• GMP & EU jurisdiction. The reassurance of European oversight — the same framework as German clinics — without Western-European pricing.
• Travel made clear. Our travel calculator shows your full cost from your city, including flights and hotel.
• One clinic, ten languages. Support and documentation in your own language, with remote follow-up after you return home.

Recovery & the Bulgarian climate

Bulgaria is more than a treatment location. Its mild, almost-Mediterranean Black Sea climate, clean air and exceptional mineral-spring tradition make it a recognised rehabilitation destination — a calmer setting to recover between or after sessions, which matters for chronic and inflammatory conditions like Primary Immunodeficiency.

What a Primary Immunodeficiency programme costs

A Primary Immunodeficiency programme at Stem Plus is €3,000–€8,000, all-in for treatment, with a fixed written quote after your medical review. See the full breakdown and country comparison on the Primary Immunodeficiency cost page.

Common questions

• Which immunodeficiencies are considered?
• Is this a transplant?
• What is the assessment?
• EU cost?

Read all Primary Immunodeficiency FAQs → · Primary Immunodeficiency cost breakdown →

Educational information only. Outcomes vary by patient. Discuss suitability with a qualified physician.